HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridinium chloride → (+/-)-cis-7-Hydroxy-3-phenyl-4-(4-(2-piperidinoethoxy)phenyl)chromane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridinium chloride | HCID 10176127 | — |
| Reactant | HCID 69930814 | HCID 69930814 | — |
| Product | (+/-)-cis-7-Hydroxy-3-phenyl-4-(4-(2-piperidinoethoxy)phenyl)chromane | HCID 69964308 | — |
Reaction Steps
In an manner analogous to that described in step 5 for Example 10, (±)-cis-7-methoxy-3-phenyl-4-(4-(2-piperidinoethoxy)phenyl)chromane (0.89 g, 2.0 mmol) was de-methylated by heating with pyridine hydrochloride to give the title compound as an off-white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06316494B1 |
| Source dataset | uspto-grants-2001_11 |
| ORD ID | ord-29abe1c5ae1f498e81e700006d6f63a9 |
| Source note | uspto-grants-2001_11 |