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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 42949Generated: October 27, 2026

2-Methyl-5-(3-trifluoromethylphenyl)oxazole-4-carboxylic acid → 2-Methyl-5-(3-trifluoromethyl-phenyl)-oxazole-4-carboxylic acid [2-(4-acetyl-thiazol-2-ylmethyl)-2H-[1,2,3]triazol-4-yl]-amide

https://huagongshe.com/reaction/42949

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-5-(3-trifluoromethylphenyl)oxazole-4-carboxylic acidHCID 66929116—
Reactant2-[4-(2-Methyl-[1,3]dioxolan-2-yl)-thiazol-2-ylmethyl]-2H-[1,2,3]triazol-4-ylamineHCID 67365122—
Product2-Methyl-5-(3-trifluoromethyl-phenyl)-oxazole-4-carboxylic acid [2-(4-acetyl-thiazol-2-ylmethyl)-2H-[1,2,3]triazol-4-yl]-amideHCID 42644154—

Reaction Steps

Following general procedure A followed by B, starting from 2-[4-(2-methyl-[1,3]dioxolan-2-yl)-thiazol-2-ylmethyl]-2H-[1,2,3]triazol-4-ylamine and 2-methyl-5-(3-trifluoromethyl-phenyl)-oxazole-4-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08536209B2
Source datasetuspto-grants-2013_09
ORD IDord-2aae5ddc0cf4442ba8a2b2f504681840
Source noteuspto-grants-2013_09