HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → 2-methoxy-5-(4H-triazol-4-yl)benzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 2-methoxy-5-(4H-triazol-4-yl)benzoic acid | HCID 18464473 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2-methoxy-5-(4H-triazol-4-yl)benzoyl chloride | HCID 18354451 | — |
Reaction Steps
Combine 2-methoxy-5-(4H-triazol-4-yl)benzoic acid (5 mmol) and dichloromethane (40 mL). Add dropwise oxalyl chloride (0.72 mL, 8.25 mmol) followed by dimethylformamide (3 drops). After 4 hours, evaporate in vacuo and dry to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06316445B1 |
| Source dataset | uspto-grants-2001_11 |
| ORD ID | ord-38e20b4a66fd44eb8d0582c240a99fca |
| Source note | uspto-grants-2001_11 |