反应详情

To a solution of 1-isopropyl-5-aminobenzimidazole (0.70 g, 3.7 mmol) and Hg(OAc)2 (2.1 g, 5.6 mmol) in 10 ml of AcOH was added solution of I2 in AcOH until it produces a precipitation; The reaction mixture was concentrated in vacuo to provide a brown solid which was subjected to column chromatography (5% NH3 sat'd MeOR/CH2Cl2) to provide 0.40 g (1.3 mmol, 35%) of the product.

1. customproduces
2. customa precipitation
3. concentrationThe reaction mixture was concentrated in vacuo
4. customto provide a brown solid which