Potassium Permanganate → HCID 70029514, compound

HRID 429773Notes

Reaction equation

HRID 429773 reaction equation
[Mn]([O-])(=O)(=O)=[O:2].[K+].[CH:7]([C:9]1[CH:10]=[CH:11][C:12]2[S:16][CH:15]=[C:14]([CH2:17][CH2:18][NH:19][C:20]([CH:22]3[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]3)=[O:21])[C:13]=2[CH:28]=1)=[O:8]>CC(C)=O.O.CC(C)=O>[CH:22]1([C:20]([NH:19][CH2:18][CH2:17][C:14]2[C:13]3[CH:28]=[C:9]([C:7]([OH:2])=[O:8])[CH:10]=[CH:11][C:12]=3[S:16][CH:15]=2)=[O:21])[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]1

Participants

5

Reactant 2

HCID 516875Potassium PermanganateHCID 18007946HCID 18007946, compound

Product 1

HCID 70029514HCID 70029514, compound

Reagents, catalysts & solvents 2

HCID 180AcetoneSolventHCID 18366337Propan-2-one--water (1/1)Solvent

Procedure

2.7 g of potassium permanganate in 50 ml of an acetone/water mixture (50/50) are added at room temperature to a solution of 6.88 mmol of the product obtained in Step E in 30 ml of acetone. The solution is stirred for 2 hours at room temperature and then filtered. The filtrate is concentrated under reduced pressure and chromatographed over silica gel to yield the title product.

Workup

  1. filtrationfiltered
  2. concentrationThe filtrate is concentrated under reduced pressure
  3. customchromatographed over silica gel

Sources & evidence

ORD record
ord-4c0c074cbd2b4d33ab9893bf53fd7c4c
Source dataset
uspto-grants-2001_11
Patent number
US06319930B1

Reaction notes

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