Morpholine → HCID 15907531, compound

HRID 429789Notes

Reaction equation

HRID 429789 reaction equation
[CH2:1]([N:3]1[C:11]2[N:10]=[C:9]([CH2:12][CH3:13])[NH:8][C:7]=2[C:6](=S)[NH:5][C:4]1=[S:15])[CH3:2].[NH:16]1[CH2:21][CH2:20][O:19][CH2:18][CH2:17]1>CC(C)=O>[CH2:1]([N:3]1[C:11]2[N:10]=[C:9]([CH2:12][CH3:13])[NH:8][C:7]=2[C:6]([N:16]2[CH2:21][CH2:20][O:19][CH2:18][CH2:17]2)=[N:5][C:4]1=[S:15])[CH3:2]

Participants

4

Reactant 2

HCID 8083MorpholineHCID 15907530HCID 15907530, compound

Product 1

HCID 15907531HCID 15907531, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

The product of stage (i) (14.42 g) was refluxed in 78.4 ml (900 mmoles) of morpholine for 30 hours. After cooling to room temperature the region product was suspended in 100 ml of acetone and the title product (16.49 g) collected and washed.

Workup

  1. customthe title product (16.49 g) collected
  2. washwashed

Sources & evidence

ORD record
ord-3138ab97871c4d47a72617100e8c48c7
Source dataset
uspto-grants-2001_11
Patent number
US06319928B1

Reaction notes

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