HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → Diethyl propylmalonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | 4-Methoxybenzaldehyde | HCID 31244 | — |
| Product | Diethyl propylmalonate | HCID 16552 | — |
Reaction Steps
TLC analysis: Silica gel 60 F254 on aluminum sheet. Eluent is mixture from petroleum ether with diethyl ether (9:1 v/v). Chromatogram is sprinkled by indicator spray and then is charred at 150° C. Composition of indicator spray: 4-methoxybenzaldehyde (10 ml), ethanol (200 ml), 98% H2SO4 (10 ml) and glacial acetic acid (2 ml). One spot. Rf 0.54.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06319952B1 |
| Source dataset | uspto-grants-2001_11 |
| ORD ID | ord-f3b7e336d77444deb7985518fc20dcc5 |
| Source note | uspto-grants-2001_11 |