HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → HCID 45358729, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 4-((((Pyridin-3-ylmethoxy)carbonyl)amino)methyl)benzoic acid | HCID 9817338 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 45358729 | HCID 45358729 | — |
Reaction Steps
0.8 ml of N,N-dimethylformamide was added to a toluene suspension (2000 ml) including 40 g (0.14 mole) of 4-[N-(pyridin-3-ylmethoxycarbonyl)aminomethyl]benzoic acid. Then, 24 ml of oxalyl chloride were added dropwise to the resultant mixture, followed by stirring for 4 hours. A deposited white solid was collected by filtration to obtain 47.7 g (quantitative) of 4-[N-(pyridin-3-ylmethoxycarbonyl)aminomethyl]benzoyl chloride hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06320078B1 |
| Source dataset | uspto-grants-2001_11 |
| ORD ID | ord-898a6c29c20842dbabb4a77f9eee5138 |
| Source note | uspto-grants-2001_11 |