HCID 18353746, compound → HCID 70196560, compound

Participants

Reaction Steps

2-{2-[1-(3,4-Dichlorobenzyl)-1.2,3,6-tetrahydropyridin-2-yl]ethylamino}-1H-quinolin-4-one (62 mg, 0.15 mmol) dissolved in ethanol (15 mL) was hydrogenated over platinum dioxide for 24 h at room temperature and atmospheric pressure. The reaction mixture was filtered and evaporated to yield the title compound as a colourless gum. δH (CD3OD) 1.16-1.80 (8H, m), 2.33-2.51 (1H, m), 2.57-2.71 (1H, m), 2.81-2.96 (1H, m), 3.16-3.37 (2H, m), 3.71-3.88 (2H, m), 5.55 (1H, s), 7.44-7.69 (6H, m,), 7.97 (1H, d, J=7.78 Hz); MS (ES+) 430 (100%) MH+.

Provenance & Evidence