HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → 5-Acetamido-phthalide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 5-Aminophthalide | HCID 720669 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 5-Acetamido-phthalide | HCID 590968 | — |
Reaction Steps
3 g of 5-amino-phthalide, 10 ml of acetic anhydride and 30 ml of tetrahydrofuran are refluxed for 1 hour. The crystals that are precipitated after cooling are suctioned off and washed with isopropylether. 3.3 g of the title compound is obtained, flash point >300° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06323199B1 |
| Source dataset | uspto-grants-2001_11 |
| ORD ID | ord-1310c23c3ad54c2b9f9a571c78bfeef0 |
| Source note | uspto-grants-2001_11 |