HCID 18351376, compound → HCID 18351382, compound

Participants

Reaction Steps

A solution of 13.4 g of the product obtained in Step C in 130 ml of tetrahydrofuran is added, at a reaction mixture temperature of 20° C., to a suspension of 3.63 g of lithium aluminium hydride in 20 ml of tetrahydrofuran. After 9 hours' reflux and then 12 hours at room temperature, the reaction mixture is hydrolysed, filtered and then concentrated under reduced pressure, enabling the expected product to be isolated.

Provenance & Evidence