Tert-butyl 4-(3,4-dichlorobenzylidene)piperidine-1-carboxylate → 1-(Tert-butoxycarbonyl)-4-(3,4-dichlorobenzyl)piperidine

Participants

Reaction Steps

Platinum oxide (0.3 g) was added to a solution of 1-(tert-butoxycarbonyl)-4-(3,4-dichlorobenzylidene)piperidine (29 g, 84.7 mmol) in ethyl acetate (500 ml) and the mixture was stirred under a hydrogen atmosphere overnight. The reaction mixture was filtered through celite and the filtrate was concentrated to give 1-(tert-butoxycarbonyl)4-(3,4-dichlorobenzyl)piperidine (30 g) as a tan oil.

Provenance & Evidence