HRID43083

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID936738

4-(4-ethylpiperazin-1-yl)aniline

C12H19N3

结构：CCN1CCN(c2cccc(NC(=O)c3ccc(-c4cncc5ccccc45)c4nccnc34)c2)CC1

HCID44515669

未命名化合物

PRODUCTS

生成物

结构：CCN1CCN(c2ccc(NC(=O)c3ccc(-c4cncc5ccccc45)c4nccnc34)cc2)CC1

HCID59292831

未命名化合物

PROCEDURE

实验过程

The title compound was prepared in analogy to the procedure described in Step 14.1 but using 4-(4-ethylpiperazin-1-yl)-aniline (Step 1.9) and 8-isoquinolin-4-yl-quinoxaline-5-carboxylic acid (Example 52). Title compound: ESI-MS: 489.1 [M+H]+; tR=10.58 min (System 2).

WORKUP

后处理

customThe title compound was prepared in analogy to the procedure

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-25ef8074833d4f0a8adbb30c3981fa5a
来源数据集: uspto-grants-2013_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08536175B2
来源说明: uspto-grants-2013_09

反应 SMILES

[CH2:1]([N:3]1[CH2:8][CH2:7][N:6]([C:9]2[CH:15]=[CH:14][C:12]([NH2:13])=[CH:11][CH:10]=2)[CH2:5][CH2:4]1)[CH3:2].C(N1CCN(C2C=C(N[C:31]([C:33]3[C:34]4[N:35]=[CH:36][CH:37]=[N:38][C:39]=4[C:40]([C:43]4[C:52]5[C:47](=[CH:48][CH:49]=[CH:50][CH:51]=5)[CH:46]=[N:45][CH:44]=4)=[CH:41][CH:42]=3)=[O:32])C=CC=2)CC1)C>>[CH2:1]([N:3]1[CH2:4][CH2:5][N:6]([C:9]2[CH:15]=[CH:14][C:12]([NH:13][C:31]([C:33]3[C:34]4[N:35]=[CH:36][CH:37]=[N:38][C:39]=4[C:40]([C:43]4[C:52]5[C:47](=[CH:48][CH:49]=[CH:50][CH:51]=5)[CH:46]=[N:45][CH:44]=4)=[CH:41][CH:42]=3)=[O:32])=[CH:11][CH:10]=2)[CH2:7][CH2:8]1)[CH3:2]