HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 430839Generated: October 26, 2026
Tetrahydrofuran → 1-Butyl-2-ethoxycarbonyl-3-propylaziridine
https://huagongshe.com/reaction/430839
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | Ethyl diazoacetate | HCID 12192 | — |
| Reactant | N-Butylidenebutylamine | HCID 94840 | — |
| Catalyst | Chlorobis(cyclooctene)iridium(I) dimer | HCID 91972094 | — |
| Product | 1-Butyl-2-ethoxycarbonyl-3-propylaziridine | HCID 9815752 | 29% |
Reaction Steps
A mixture of 0.5 mmol of N-butylidenebutylamine, 0.5 mmol of ethyl diazoacetate, 0.015 mmol of di-μ-chlorotetrakis(cyclooctene)diiridium(I) [Ir2Cl2(cyclooctene)4], and 0.5 ml of tetrahydrofuran was stirred at room temperature (25° C.) in an argon atmosphere for 3 hours. As a result, 1-butyl-2-ethoxycarbonyl-3-propylaziridine was obtained in a yield of 29%. Small amounts of diethyl fumarate and diethyl maleate were formed as by-products.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06323346B1 |
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| Source dataset | uspto-grants-2001_11 |
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| ORD ID | ord-6e7a4d19e44a4ea29ed762568d827514 |
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| Source note | uspto-grants-2001_11 |
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