反应详情

A mixture of 2.77g of 3-phenylcycloheptanone, 2.52 g of methylphenethylamine hydrochloride and 1.23 ml of an aqueous formaldehyde solution (36%) were heated on a water bath for 2 hours under vigorous stirring and with the introduction of nitrogen. The mixture was then evaporated under vacuum, the residue was extracted 3 times with diethylether/n-hexane=1/1 and dried under vacuum. 5.4 g of the crude title compound were then obtained.

1. temperaturewere heated on a water bath for 2 hours
2. customThe mixture was then evaporated under vacuum
3. extractionthe residue was extracted 3 times with diethylether/n-hexane=1/1
4. customdried under vacuum