反应详情

温度

0 °C

To a solution of 2-methyl-5-nitrobenzimidazole in concentrated sulfuric acid was added fuming nitric acid at −5° C. Upon addition of the fuming nitric acid, the reaction mixture was warmed to 0° C. held for 1 h and poured into crushed ice. The precipitate which formed was filtered, washed with water, and dried overnight at 40° C. to give the title compound.

1. customat −5° C
2. additionpoured
3. custominto crushed ice
4. customThe precipitate which formed
5. filtrationwas filtered
6. washwashed with water
7. customdried overnight at 40° C.