4,4'-Dibromobenzil → HCID 9957901, compound

HRID 430997Notes

Reaction equation

HRID 430997 reaction equation
[CH3:1][N:2]1[C:6]2[CH:7]=[C:8]([NH2:12])[C:9]([NH2:11])=[CH:10][C:5]=2[N:4]=[C:3]1[CH3:13].[Br:14][C:15]1[CH:20]=[CH:19][C:18]([C:21]([C:23]([C:25]2[CH:30]=[CH:29][C:28]([Br:31])=[CH:27][CH:26]=2)=O)=O)=[CH:17][CH:16]=1>CO>[CH3:1][N:2]1[C:6]2=[CH:7][C:8]3[N:12]=[C:21]([C:18]4[CH:19]=[CH:20][C:15]([Br:14])=[CH:16][CH:17]=4)[C:23]([C:25]4[CH:26]=[CH:27][C:28]([Br:31])=[CH:29][CH:30]=4)=[N:11][C:9]=3[CH:10]=[C:5]2[N:4]=[C:3]1[CH3:13]

Participants

4

Reactant 2

HCID 964304,4'-DibromobenzilHCID 5297144HCID 5297144, compound

Product 1

HCID 9957901HCID 9957901, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a solution of 1,2-dimethyl-5,6-diaminobenzoimidazole in methanol was added 4,4′-dibromo-benzil. The reaction mixture was refluxed for 3 h and cooled to room temperature. The precipitate which formed was filtered and recrystallized from n-butyl alcohol to give the title quinoxaline.

Workup

  1. temperatureThe reaction mixture was refluxed for 3 h
  2. customThe precipitate which formed
  3. filtrationwas filtered
  4. customrecrystallized from n-butyl alcohol

Sources & evidence

ORD record
ord-c3112108727d4021a9313ed8fd6debb0
Source dataset
uspto-grants-2003_12
Patent number
US06656940B2

Reaction notes

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