HCID 10760311, compound → 3-(1-Benzothien-3-yl)-8-{[(2s)-8-methoxy-2,3-dihydro-1,4-benzodioxin-2-yl]methyl}-8-azabicyclo[3.2.1]octan-3-ol

Participants

Reaction Steps

The title compound was prepared by the same procedure described in Example 1, Step 4 using 3-benzo[b]thiophen-3-yl-8-aza-bicyclo[3.2.1]octan-3-ol in place of 3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]octan-3-ol, and (S)-toluene-4-sulfonic acid 8-methoxy-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl ester in place of (S)-toluene-4-sulfonic acid 8-ethoxy-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl ester. Yield: 33%, white solid.

Provenance & Evidence