Water → HCID 86759277, compound

Participants

Reaction Conditions

Reaction Steps

To a reaction mixture containing the (Z)-styryl 2-hydroxyphenylsulfide (5 mmol), anhydrous pyridine (5 mmol) and acetic anhydride (5 mmol) in dry chloroform (10 ml) is stirred for 5 hours at room temperature (22° C.). The reaction mixture is then diluted with water (20 ml) and shaken well in a separating funnel. The lower organic layer is collected and dried over anhydrous sodium sulfate. Evaporation of the chloroform in vacuum yields the corresponding (Z)-styryl 2-acetoxyphenylsulfide (I) as an oil, or in most cases a colorless solid. The products are purified by TLC or by fractional crystallization.

Provenance & Evidence