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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 431140Generated: November 1, 2026

2,4-Difluorobenzaldehyde → E-2,4-difluorostyryl 4-fluorobenzyl sulfone

https://huagongshe.com/reaction/431140

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DifluorobenzaldehydeHCID 73770—
Reactant[(4-Fluorobenzyl)sulfonyl]acetic acidHCID 11447598—
ProductE-2,4-difluorostyryl 4-fluorobenzyl sulfoneHCID 988323268%

Reaction Steps

A solution of 4-fluorobenzyl sulfonylacetic acid (0.01 mol) and 2,4-difluorobenzaldehyde (0.01 mol) was subjected to Procedure 1, Part B. The title compound was obtained in 68% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06656973B2
Source datasetuspto-grants-2003_12
ORD IDord-a55888cb885147258e63ea9a7ba593b5
Source noteuspto-grants-2003_12