4-Fluorobenzaldehyde → 2-(Benzenesulfonyl)-3-(4-fluorophenyl)-1-phenylprop-2-en-1-one

HRID 431162Notes

Reaction equation

HRID 431162 reaction equation
[CH2:1]([S:10]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)(=[O:12])=[O:11])[C:2]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)=[O:3].[F:19][C:20]1[CH:27]=[CH:26][C:23]([CH:24]=O)=[CH:22][CH:21]=1>>[C:13]1([S:10]([C:1](=[CH:24][C:23]2[CH:26]=[CH:27][C:20]([F:19])=[CH:21][CH:22]=2)[C:2]([C:4]2[CH:5]=[CH:6][CH:7]=[CH:8][CH:9]=2)=[O:3])(=[O:11])=[O:12])[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

3

Reactant 2

HCID 680234-FluorobenzaldehydeHCID 769491-Phenyl-2-(phenylsulphonyl)ethan-1-one

Product 1

HCID 669379392-(Benzenesulfonyl)-3-(4-fluorophenyl)-1-phenylprop-2-en-1-oneYield 62%

Procedure

A solution of phenacylphenyl sulfone (0.01 mol) and 4-fluorobenzaldehyde (0.01 mol) was subjected to Method 1 of Procedure 4. The title compound, melting point 142-143° C., was obtained in 62% yield.

Sources & evidence

ORD record
ord-89631d530b824fb1a08ea0aeb32bb44b
Source dataset
uspto-grants-2003_12
Patent number
US06656973B2

Reaction notes

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