HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Aminothiazole → (2,6-Dimethyl-phenyl)-(6-pyridin-4-yl-imidazo[2,1-b]thiazol-5-yl)-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Aminothiazole | HCID 2155 | — |
| Reactant | 4-Pyridinecarboxaldehyde | HCID 13389 | — |
| Reactant | 2,6-Dimethylphenyl isocyanide | HCID 76009 | — |
| Solvent | Perchloric Acid | HCID 24247 | — |
| Product | (2,6-Dimethyl-phenyl)-(6-pyridin-4-yl-imidazo[2,1-b]thiazol-5-yl)-amine | HCID 22335557 | — |
Reaction Steps
Compound 21 was prepared in accordance with the general synthesis instructions from 1.0 ml (0.1 mmol) 2-aminothiazole solution (0.1 M, MC), 0.575 ml (0.115 mmol) 2,6-dimethylphenylisonitrile solution (0.2 M, MC), 0.500 ml (0.15 mmol) 4-pyridinecarbaldehyde solution (0.3 M, MC) and 10 μl perchloric acid (w=20%) in a substance library.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06657064B2 |
| Source dataset | uspto-grants-2003_12 |
| ORD ID | ord-f6405ee748aa444082c3473abc29cd5b |
| Source note | uspto-grants-2003_12 |