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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 431221Generated: October 28, 2026

Benzaldehyde → HCID 9796853, compound

https://huagongshe.com/reaction/431221

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzaldehydeHCID 240—
Reactant2-AminothiazoleHCID 2155—
ReactantAcetyl chlorideHCID 6367—
ReactantTert-Butyl isocyanideHCID 23577—
SolventPerchloric AcidHCID 24247—
ProductHCID 9796853HCID 9796853—

Reaction Steps

Compound 40 was prepared in accordance with the general synthesis instructions from 1.0 ml (0.1 mmol) 2-amino thiazole solution (0.1 M, MC), 0.575 ml (0.115 mmol) tert-butylisonitrile solution (0.2 M, MC), 0.500 ml (0.15 mmol) benzaldehyde solution (0.3 M, MC) and 10 μl perchloric acid (w=20%) and by reaction with acetyl chloride, the excess acetyl chloride being removed in vacuo.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06657064B2
Source datasetuspto-grants-2003_12
ORD IDord-2b8e7534b892483abc65e080922baf49
Source noteuspto-grants-2003_12