HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Aminothiazole → Cyclohexyl-[6-(2,5-dimethylphenyl)-imidazo[2,1-b]thiazol-5-yl]-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Aminothiazole | HCID 2155 | — |
| Reactant | 2,5-Dimethylbenzaldehyde | HCID 22015 | — |
| Reactant | Cyclohexyl isocyanide | HCID 79129 | — |
| Solvent | Perchloric Acid | HCID 24247 | — |
| Product | Cyclohexyl-[6-(2,5-dimethylphenyl)-imidazo[2,1-b]thiazol-5-yl]-amine | HCID 22335571 | — |
Reaction Steps
Compound 51 was prepared in accordance with the general synthesis instructions from 1.0 ml (0.1 mmol) 2-amino thiazole solution (0.1 M, MC), 0.575 ml (0.115 mmol) cyclohexylisonitrile solution (0.2 M, MC), 0.500 ml (0.15 mmol) 2,5-dimethylbenzaldehyde solution (0.3 M, MC) and 10 μl perchloric acid (w=20%) in a substance library.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06657064B2 |
| Source dataset | uspto-grants-2003_12 |
| ORD ID | ord-fec350a9ff16484ea6572d95db4d29ec |
| Source note | uspto-grants-2003_12 |