2-(Benzenesulfonyl)-3-phenyloxaziridine → HCID 22397096, compound

Participants

Reaction Steps

A mixture of 2-(2-ethylsulfanyl-ethyl)-5-(4-fluoro-benzyloxy)-isoindole-1,3-dione (96 mg, 0.27 mmol) and 3-phenyl-2-(phenylsulfonyl)oxaziridine (84 mg, 0.32 mmol) in CH2Cl2 (3 mL) was stirred at room temperature for 72 h. Then the mixture was evaporated and the residue was purified by chromatography (SiO2, CH2Cl2:2N NH3/MeOH 97:3 to 9:1) to afford the title compound (34 mg, 34%) as a white solid. MS: m/e=375.2 (M+H+).

Provenance & Evidence