4-Piperidinecarboxylic acid → 2-(Piperidin-4-yl)-1,3-benzoxazole

HRID 431630Notes

Reaction equation

HRID 431630 reaction equation
[NH:1]1[CH2:9][CH2:8][CH:4]([C:5]([OH:7])=O)[CH2:3][CH2:2]1.[NH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1O>>[O:7]1[C:12]2[CH:13]=[CH:14][CH:15]=[CH:16][C:11]=2[N:10]=[C:5]1[CH:4]1[CH2:3][CH2:2][NH:1][CH2:9][CH2:8]1

Participants

3

Reactant 2

HCID 37734-Piperidinecarboxylic acidHCID 58012-Aminophenol

Product 1

HCID 7704612-(Piperidin-4-yl)-1,3-benzoxazole

Procedure

The title compound was prepared from isonipecotic acid and 2-aminophenol using the method described in Description 14. MH+ 203.

Sources & evidence

ORD record
ord-7127d39f13a6431bbd93977ff5fac058
Source dataset
uspto-grants-2003_12
Patent number
US06660751B1

Reaction notes

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