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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 431633Generated: October 30, 2026

4-Chloro 2,5-dimethylbenzenesulfonic Acid 2-(isopropyl-(4-chloro 2,5-dimethylbenzenesulfonyl)-amino)-ethyl Ester → 4-Chloro-2,5-dimethyl-N-(2-(4-(5fluoro-1H-benzimidazol-2-yl)-piperidin-1-yl)-ethyl)-N-isopropyl Benzene Sulfonamide

https://huagongshe.com/reaction/431633

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloro 2,5-dimethylbenzenesulfonic Acid 2-(isopropyl-(4-chloro 2,5-dimethylbenzenesulfonyl)-amino)-ethyl EsterHCID 53739930—
Reactant6-Fluoro-2-(piperidin-4-yl)-1H-benzimidazoleHCID 178505464—
Product4-Chloro-2,5-dimethyl-N-(2-(4-(5fluoro-1H-benzimidazol-2-yl)-piperidin-1-yl)-ethyl)-N-isopropyl Benzene SulfonamideHCID 178429737—

Reaction Steps

The title compound was prepared using the procedure described in Example 1 using D8 and 4-(5-fluoro-1H-benzimidazol-2-yl)piperidine (D17). MH+ 507/509.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06660751B1
Source datasetuspto-grants-2003_12
ORD IDord-86979db3c27c4b97bbb8a55680d577b1
Source noteuspto-grants-2003_12