4,5-Dichloro-n-(2-chloroethyl)-n-methyl-2-trifluoromethyl-benzenesulfonamide → HCID 178484207, compound

HRID 431637Notes

Reaction equation

HRID 431637 reaction equation
[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][C:5]([S:9]([N:12]([CH2:14][CH2:15]Cl)[CH3:13])(=[O:11])=[O:10])=[C:4]([C:17]([F:20])([F:19])[F:18])[CH:3]=1.[F:21][C:22]1[CH:36]=[CH:35][C:25]2[NH:26][C:27]([CH:29]3[CH2:34][CH2:33][NH:32][CH2:31][CH2:30]3)=[N:28][C:24]=2[CH:23]=1>>[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][C:5]([S:9]([N:12]([CH2:14][CH2:15][N:32]2[CH2:31][CH2:30][CH:29]([C:27]3[NH:26][C:25]4[CH:35]=[CH:36][C:22]([F:21])=[CH:23][C:24]=4[N:28]=3)[CH2:34][CH2:33]2)[CH3:13])(=[O:11])=[O:10])=[C:4]([C:17]([F:20])([F:19])[F:18])[CH:3]=1

Participants

3

Reactant 2

HCID 187615234,5-Dichloro-n-(2-chloroethyl)-n-methyl-2-trifluoromethyl-benzenesulfonamideHCID 1785054646-Fluoro-2-(piperidin-4-yl)-1H-benzimidazole

Product 1

HCID 178484207HCID 178484207, compound

Procedure

The title compound was prepared using the procedure described in Example 1 using 4,5-dichloro-N-(2-chloroethyl)-N-methyl-2-trifluoromethyl-benzenesulfonamide (D12) and 4-(5-fluoro 1H benzimidazol-2-yl)piperidine (D17). MH+ 581/583/585.

Sources & evidence

ORD record
ord-356338e4f8a148c98bb723b82af3404e
Source dataset
uspto-grants-2003_12
Patent number
US06660751B1

Reaction notes

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