E-7-Phenylhept-4-enoic acid → 7-Phenyl heptanoic acid

HRID 431815Notes

Reaction equation

HRID 431815 reaction equation
[C:1]1([CH2:7][CH2:8]/[CH:9]=[CH:10]/[CH2:11][CH2:12][C:13]([OH:15])=[O:14])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1>[Pd]>[C:1]1([CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][C:13]([OH:15])=[O:14])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 1

HCID 9899164E-7-Phenylhept-4-enoic acid

Product 1

HCID 5209877-Phenyl heptanoic acid

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

7-Phenylheptanoic acid was prepared from E-7-phenylhept-4-enoic acid by hydrogenation at 40 psi using 5% palladium on carbon as the catalyst. Quantitative conversion of the alkene to the alkane was observed by thin layer chromatographic analysis. The product acid was purified by chromatography on silica gel and fully characterized by spectroscopic methods (infrared and nuclear magnetic resonance) and combustion analysis.

Workup

  1. customThe product acid was purified by chromatography on silica gel

Sources & evidence

ORD record
ord-de60b131fe3e4875a3cef8cbd4903e30
Source dataset
uspto-grants-2003_12
Patent number
US06660770B2

Reaction notes

Loading…