HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromopyridine → 2-(2-Ethenylphenyl)pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromopyridine | HCID 7973 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-Vinylbenzeneboronic acid | HCID 2773587 | — |
| Catalyst | Tetrakis(triphenylphosphine)palladium | HCID 11979704 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-(2-Ethenylphenyl)pyridine | HCID 69740 | 75% |
Reaction Steps
The reaction was performed with 2-vinyl-phenylboronic acid (10 g, 0.0676 mol), 2-bromopyridine (12.64 g, 0.08 mol), tetrahydrofuran (100 ml), 2M potassium carbonate aqueous solution (26 ml), and tetrakis(triphenylphosphine) palladium (Pd(Ph3)4, 0.06 g, 1 mol %) according to Example 1. The yield was 75%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06660821B2 |
| Source dataset | uspto-grants-2003_12 |
| ORD ID | ord-c31ac0fae9a0431ea5eaabf15e571f45 |
| Source note | uspto-grants-2003_12 |