Cyanogen Bromide → HCID 86759299, compound

Participants

Reaction Steps

1-(2-tert-Butoxy carbonyl aminopropyl)-2-aminobenzimidazole hydrobromide was prepared by the method of Example 1 using 2-tert-butoxycarbonyl aminopropylamine and 2-fluoro-nitrobenzene as starting materials. The cyclization reaction using cyanogen bromide gave the desired material as a solid which was collected by filtration MS 290 (M+1). 1H NMR (DMSO): δ 0.74 (s, 9H,) 0.96 (d, 3H), 3.67 (m, 3H), 6.57 (d, 1H), 7.03(m, 3H), 8.44 (s, 2H, NH2), 12.35 (broad s, NH).

Provenance & Evidence