4-Methylbenzoyl Chloride → HCID 12106079, compound

HRID 432040Notes

Reaction equation

HRID 432040 reaction equation
[CH2:1]([N:3]([CH2:6][CH2:7][N:8]1[C:12]2[CH:13]=[C:14]([O:17][CH3:18])[CH:15]=[CH:16][C:11]=2[N:10]=[C:9]1[NH2:19])[CH2:4][CH3:5])[CH3:2].[CH3:20][C:21]1[CH:29]=[CH:28][C:24]([C:25](Cl)=[O:26])=[CH:23][CH:22]=1>>[CH2:1]([N:3]([CH2:6][CH2:7][N:8]1[C:12]2[CH:13]=[C:14]([O:17][CH3:18])[CH:15]=[CH:16][C:11]=2[N:10]=[C:9]1[NH:19][C:25](=[O:26])[C:24]1[CH:28]=[CH:29][C:21]([CH3:20])=[CH:22][CH:23]=1)[CH2:4][CH3:5])[CH3:2]

Participants

3

Reactant 2

HCID 134054-Methylbenzoyl ChlorideHCID 69941611HCID 69941611, compound

Product 1

HCID 12106079HCID 12106079, compound

Procedure

1-(N,N-Diethylaminoethyl)-2-(4-methylbenzamido)-6-methoxybenzimidazole was prepared by the method of Example 2 using 1-(N,N-diethylaminoethyl)-2-amino-6-methoxybenzimidazole and 4-methylbenzoyl chloride. 1H NMR (DMSO): δ 1.33(t, 6H), 2.51 (s, CH3 ar), 3.40 (m, 4H), 3.58 (m, 2H), 3.98 (s, 3H), 4.87 (m 2H), 6.99-8.28 (4 m, 7 H), 11.61 (broad s, NH).

Sources & evidence

ORD record
ord-7885df4a39234d0e907b67792e025b0a
Source dataset
uspto-grants-2003_12
Patent number
US06660870B1

Reaction notes

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