Benzoyl chloride → HCID 69940670, compound

HRID 432041Notes

Reaction equation

[C:1]([Cl:9])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:10][N:11]([CH2:13][CH2:14][N:15]1[C:19]2[CH:20]=[CH:21][CH:22]=[CH:23][C:18]=2[N:17]=[C:16]1[NH2:24])[CH3:12]>>[ClH:9].[CH3:12][N:11]([CH2:13][CH2:14][N:15]1[C:19]2[CH:20]=[CH:21][CH:22]=[CH:23][C:18]=2[N:17]=[C:16]1[NH:24][C:1](=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)[CH3:10]

Participants

Reactant 2

HCID 7412Benzoyl chloride

HCID 745066HCID 745066, compound

Product 1

HCID 69940670HCID 69940670, compound

Procedure

1-(N,N-Dimethylaminoethyl)-2-benzamidobenzimidazole hydrochloride was prepared by the method of Example 1 using benzoyl chloride and 1-(N,N-dimethylaminoethyl)-2-aminobenzimidazole. MS 308 (M+1). 1H NMR (DMSO): δ 2.92 (s, 3H), 2.94 (s, 3H), 3.60 (m, 2H), 4.75 (m, 2H), 7.27-8.33 (m, 9H), 10.81 (broad s, NH).

Sources & evidence

ORD record: ord-aa7784eb08da47c58412c04b3ead83d0
Source dataset: uspto-grants-2003_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06660870B1

Reaction notes

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