Ethylene → HCID 22345111, compound

Participants

Reaction Steps

A solution of 6,6′-dibromo-2,2′-dihydroxy-1,1′-binaphthyl (0.694 g, 1.56 mmol), Pd(OAc)2 (0.020 g, 5 mol %), P(o-tolyl)3 (0.080 g, 15 mol %) and Et3N (0.5 mL) in DMF (2 mL) was pressurized with ethylene (200 psi) at 75° C. for 18 hrs. The resulting mixture was diluted in ethyl acetate (20 mL) and filtered through celite, followed by water (20 mL) and brine (20 mL) washes. The solution was dried over MgSO4 and evaporated to produce a tan solid, which was purified by column chromatography to yield the desired product in 54% yield (0.286 g).

Provenance & Evidence