2,3-Difluorophenol → 3,4-Bis(4-methoxyphenyl)-6-(2,3-difluorophenoxy)pyridazine

Participants

Reaction Steps

In a similar manner as in Example 2, 3,4-bis(4-methoxyphenyl)-6-chloropyridazine (180 mg, 0.551 mmol) and 2,3-difluorophenol were reacted as starting materials at 150° C. for 19 hours and post-treatment was then conducted, whereby the title compound was obtained as a colorless crystalline powder (203.3 mg, 90.0%). Melting point: 157.5-159.0° C. (chloroform-hexane).

Provenance & Evidence