2,6-Difluorophenol → 3,4-Bis(4-methoxyphenyl)-6-(2,6-difluorophenoxy)pyridazine

Participants

Reaction Steps

In a similar manner as in Example 2, 3,4-bis(4-methoxyphenyl)-6-chloropyridazine (200 mg, 0.613 mmol) and 2,6-difluorophenol were reacted as starting materials at 150° C. for 72 hours and post-treatment was then conducted, whereby the title compound was obtained as a colorless crystalline powder (101.0 mg, 39.3%). Melting point: 204.7-206.4° C. (chloroform-hexane).

Provenance & Evidence