3,4-Difluorophenol → 3,4-Bis(4-methoxyphenyl)-6-(3,4-difluorophenoxy)pyridazine

Participants

Reaction Steps

In a similar manner as in Example 2, 3,4-bis(4-methoxyphenyl)-6-chloropyridazine (150 mg, 0.459 mmol) and 3,4-difluorophenol were reacted as starting materials at 150° C. for 14 hours and post-treatment was then conducted, whereby the title compound was obtained as a pale yellow amorphous solid (190.2 mg, 99.1%).

Provenance & Evidence