3,4-Bis(4-methoxyphenyl)-6-chloropyridazine → HCID 18759985, compound

HRID 432631Notes

Reaction equation

HRID 432631 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[N:10]=[N:11][C:12](Cl)=[CH:13][C:14]=2[C:15]2[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=2)=[CH:5][CH:4]=1.[Cl:24][C:25]1[CH:26]=[C:27]([SH:33])[CH:28]=[C:29]([Cl:32])[C:30]=1[Cl:31]>>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([C:9]2[N:10]=[N:11][C:12]([S:33][C:27]3[CH:28]=[C:29]([Cl:32])[C:30]([Cl:31])=[C:25]([Cl:24])[CH:26]=3)=[CH:13][C:14]=2[C:15]2[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=2)=[CH:7][CH:8]=1

Participants

3

Reactant 2

HCID 125680843,4-Bis(4-methoxyphenyl)-6-chloropyridazineHCID 18760004HCID 18760004, compound

Product 1

HCID 18759985HCID 18759985, compound

Procedure

In a similar manner as in Example 2, 3,4-bis(4-methoxyphenyl)-6-chloropyridazine (200 mg, 0.613 mmol) and 3,4,5-trichlorothiophenol [Ger. Offen. DE 2515699 19751023 (Dow Chemical Co., U.S.A.)] were reacted as starting materials at 100° C. for 72 hours and post-treatment was then conducted, whereby the title compound was obtained as a colorless amorphous solid (125.3 mg, 40.6%)

Workup

  1. customat 100° C.
  2. customfor 72 hours

Sources & evidence

ORD record
ord-19571ed67fa94611bf0d162e489f5901
Source dataset
uspto-grants-2003_12
Patent number
US06664256B1

Reaction notes

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