Dimethylamine → HCID 18759988, compound

HRID 432650Notes

Reaction equation

HRID 432650 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[N:10]=[N:11][C:12](Cl)=[CH:13][C:14]=2[C:15]2[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=2)=[CH:5][CH:4]=1.[CH3:24][NH:25][CH3:26]>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[N:10]=[N:11][C:12]([N:25]([CH3:26])[CH3:24])=[CH:13][C:14]=2[C:15]2[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=2)=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 674DimethylamineHCID 125680843,4-Bis(4-methoxyphenyl)-6-chloropyridazine

Product 1

HCID 18759988HCID 18759988, compound

Procedure

In a similar manner as in Example 2, 3,4-bis(4-methoxyphenyl)-6-chloropyridazine (140 mg, 0.43 mmol) and a 40% (W/V) aqueous solution of dimethylamine were reacted as starting materials at 45° C. for 30 hours and post-treatment was then conducted, whereby the title compound was obtained as colorless prisms (139 mg, 96.5%). Melting point: 109.6-110.7° C. (ethyl acetate-hexane).

Workup

  1. customat 45° C.
  2. customfor 30 hours

Sources & evidence

ORD record
ord-61490a727b774ba1bac387622512605d
Source dataset
uspto-grants-2003_12
Patent number
US06664256B1

Reaction notes

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