Acetone → HCID 86665305, compound

HRID 43274Notes

Reaction equation

HRID 43274 reaction equation
[C:1]1([S:7]([OH:10])(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH:11]1[CH2:16][CH2:15][C:14](=[C:17]2[C:26]3[CH:27]=[CH:28][CH:29]=[CH:30][C:25]=3[CH:24]=[CH:23][C:22]3[S:21][C:20]([CH:31](C)C(O)=O)=[CH:19][C:18]2=3)[CH2:13][CH2:12]1.C[C:37]([CH3:39])=[O:38]>>[C:1]1([S:7]([OH:10])(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH:11]1[CH2:16][CH2:15][C:14](=[C:17]2[C:26]3[CH:27]=[CH:28][CH:29]=[CH:30][C:25]=3[CH:24]=[CH:23][C:22]3[S:21][C:20]([CH2:31][CH2:39][C:37]([OH:8])=[O:38])=[CH:19][C:18]2=3)[CH2:13][CH2:12]1

Participants

3

Reactant 2

HCID 180AcetoneHCID 86665306HCID 86665306, compound

Product 1

HCID 86665305HCID 86665305, compoundYield 30%

Procedure

3-(4-Piperidin-4-ylidene-4H-1-thiabenzo[f]azulen-2-yl-propionic acid benzenesulfonate of 99.6% purity (1.0 g) was dissolved in acetone (50 mL) by heating and allowed to cool down to room temperature and the crystals deposited therefrom were filtered to give 0.30 g (recovery rate: 30%) of 3-(4-piperidin-4-ylidene-4H-1-thiabenzo[f]azulen-2-yl) propionic acid benzenesulfonate of 100% purity.

Workup

  1. temperatureby heating
  2. filtrationthe crystals deposited therefrom were filtered

Sources & evidence

ORD record
ord-368d7c2fc0e149a8a21ffa66657c515e
Source dataset
uspto-grants-2013_09
Patent number
US08536342B2

Reaction notes

Loading…