HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-ethyl 1-(2-thiopheneacetyl)-3-piperidinecarboxylate → (S)-1-(2-Thiopheneacetyl)-3-piperidine Carboxylic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-ethyl 1-(2-thiopheneacetyl)-3-piperidinecarboxylate | HCID 9838651 | — |
| Reactant | 1-(2-(Thiophen-2-yl)acetyl)piperidine-3-carboxylic acid | HCID 16790995 | — |
| Product | (S)-1-(2-Thiopheneacetyl)-3-piperidine Carboxylic Acid | HCID 10198935 | — |
Reaction Steps
This reaction was run in the same manner as 1-(2-thiopheneacetyl)-3-piperidine carboxylic acid, starting with (S)-ethyl 1-(2-thiopheneacetyl)-3-piperidinecarboxylate (10 g; 35.6). This gave (S)-1-(2-thiopheneacetyl)-3-piperidine carboxylic acid (9.27 g) as a white solid without further purification. MS m/z (positive ion) 506 (dimer+; 25), 254 (MH+; 100).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06664271B1 |
| Source dataset | uspto-grants-2003_12 |
| ORD ID | ord-c707a4c9e1e94e03939d667a1d9844e8 |
| Source note | uspto-grants-2003_12 |