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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 432818Generated: October 25, 2026

Benzyl chloroformate → 1-Benzyl 3-methyl 4-oxopiperidine-1,3-dicarboxylate

https://huagongshe.com/reaction/432818

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzyl chloroformateHCID 10387—
ReactantMethyl 4-oxopiperidine-3-carboxylate hydrochlorideHCID 2724028—
ReactantEthyl 1-benzoyl-3-piperidinecarboxylateHCID 3784394—
Product1-Benzyl 3-methyl 4-oxopiperidine-1,3-dicarboxylateHCID 15748136—

Reaction Steps

This compound may be prepared in the same manner as ethyl 1-benzoyl-3-piperidinecarboxylate, starting with commercially available methyl 4-oxo-3-piperidinecarboxylate hydrochloride, diisopropylethylaamine and commercially available benzyl chloroformate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06664271B1
Source datasetuspto-grants-2003_12
ORD IDord-cb9b41f38a1848d28da03e74a9eacd49
Source noteuspto-grants-2003_12