HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Sodium Hydroxide → (S)-1-benzoyl-3-piperidinecarboxylic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Sodium Hydroxide | HCID 14798 | — |
| Edukt | (S)-ethyl 1-benzoyl-3-piperidinecarboxylate | HCID 670251 | — |
| Edukt | 1-(2-(Thiophen-2-yl)acetyl)piperidine-3-carboxylic acid | HCID 16790995 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | (S)-1-benzoyl-3-piperidinecarboxylic acid | HCID 743141 | 92,7% |
Reaktionsschritte
The reaction was run in the same manner as 1-(2-thiopeneacetyl)-3-piperidine carboxylic acid, starting with (S)-ethyl 1-benzoyl-3-piperidinecarboxylate (8.71 g; 33.31 mmol), 1N sodium hydroxide (100 ml) and absolute ethanol (100 ml), giving (S)-1-benzoyl-3-piperidinecarboxylic acid as a white solid (7.20 g). MS m/z (negative ion) 232 ([M-H]−; 100).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06664271B1 |
| Quelldatensatz | uspto-grants-2003_12 |
| ORD ID | ord-e75c0336ea6648c4ad4215840a5bc935 |
| Quellennotiz | uspto-grants-2003_12 |