HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → HCID 42261313, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | (S)-1-benzoyl-3-piperidinecarboxylic acid | HCID 743141 | — |
| Reactant | N-benzoylnipecotoyl chloride | HCID 15718173 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 42261313 | HCID 42261313 | — |
Reaction Steps
The reaction was run in the same manner as 1-benzoyl-3-piperidinecarbonyl chloride, starting with (S)-1-benzoyl-3-piperidinecarboxylic acid (6.30 g; 27.0 mmols), thionyl chloride (16.06 g, 135 mmol), and dry dichloromethane (150 ml), giving (S)-1-benzoyl-3-piperidinecarbonyl chloride as a light yellow oil, which was used without further purification. MS (in CH3CN) m/z (positive ion) 503 (40), 485 (42), 467 (40), 254 (60), 252 (MH+; 100), 234 (68).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06664271B1 |
| Source dataset | uspto-grants-2003_12 |
| ORD ID | ord-7f420071fe2f4d6f8a4cda918cb08b79 |
| Source note | uspto-grants-2003_12 |