2-(Pyridin-2-YL)propanal → 4-Cyclohexyl-3-methyl-4-oxo-3-(2-pyridyl)butyraldehyde

HRID 432866Notes

Reaction equation

HRID 432866 reaction equation
[N:1]1C=CC=CC=1C(C)C=O.[CH:11]1([C:17](=[O:29])[C:18]([CH3:28])([C:22]2C=[CH:26][CH:25]=[CH:24][CH:23]=2)[CH2:19][CH:20]=[O:21])[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12]1>>[CH:11]1([C:17](=[O:29])[C:18]([CH3:28])([C:22]2[CH:23]=[CH:24][CH:25]=[CH:26][N:1]=2)[CH2:19][CH:20]=[O:21])[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12]1

Participants

3

Reactant 2

HCID 111263082-(Pyridin-2-YL)propanalHCID 117801924-Cyclohexyl-3-methyl-4-oxo-3-phenylbutanal

Product 1

HCID 120942284-Cyclohexyl-3-methyl-4-oxo-3-(2-pyridyl)butyraldehyde

Procedure

Scheme VI, steps A-D: 4-Cyclohexyl-3-methyl-4-oxo-3-(2-pyridyl)butyraldehyde is prepared from 2-(2-pyridyl)-propanaldehyde in a manner analogous to the procedure described in example 7 for the preparation of 4-cyclohexyl-3-methyl-4-oxo-3-phenylbutyraldehyde.

Sources & evidence

ORD record
ord-d7a5f32cd08845ad923b3c23d208239a
Source dataset
uspto-grants-2003_12
Patent number
US06664274B1

Reaction notes

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