Chloroform → HCID 18760547, compound

HRID 432893Notes

Reaction equation

HRID 432893 reaction equation
[CH2:1]([C:3]([NH2:11])([CH3:10])[CH2:4][NH:5][C:6]([CH3:9])([CH3:8])[CH3:7])[CH3:2].[CH3:12][C:13]([CH2:15][CH3:16])=O.[OH-:17].[Na+].[CH:19](Cl)(Cl)Cl>>[C:6]([N:5]1[CH2:12][C:13]([CH2:15][CH3:16])([CH3:19])[NH:11][C:3]([CH2:1][CH3:2])([CH3:10])[C:4]1=[O:17])([CH3:9])([CH3:8])[CH3:7]

Participants

5

Reactant 4

HCID 6212ChloroformHCID 6569Methyl Ethyl KetoneHCID 14798Sodium HydroxideHCID 18760475HCID 18760475, compound

Product 1

HCID 18760547HCID 18760547, compoundYield 100%

Procedure

In analogy to Example B23, 1-ethyl-1-methyl-2-t-butylaminoethylamin, methylethylketon, chloroform and NaOH are reacted to give the raw title compound (100%) as an yellow oil.

Sources & evidence

ORD record
ord-fe54c6d907554b9aad692153c6e4041a
Source dataset
uspto-grants-2003_12
Patent number
US06664353B2

Reaction notes

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