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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 432898Generated: October 26, 2026

Chloroform → 1-t-Butyl-3,3-dipropyl-5,5-dimethyl-piperazin-2-on

https://huagongshe.com/reaction/432898

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChloroformHCID 6212—
ReactantSodium HydroxideHCID 14798—
Reactant4-HeptanoneHCID 31246—
Reactant1,2-Propanediamine, N1-(1,1-dimethylethyl)-2-methyl-HCID 12580989—
Product1-t-Butyl-3,3-dipropyl-5,5-dimethyl-piperazin-2-onHCID 18760555—

Reaction Steps

In analogy to Example B21, 1,1-dimethyl-2-t-butylaminoethylamin, dipropylketon, chloroform and NaOH are reacted to give the title compound as a yellow oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06664353B2
Source datasetuspto-grants-2003_12
ORD IDord-17810f044e8547db8e4c695ed9a82702
Source noteuspto-grants-2003_12