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4-(3-Bromo-4-methoxyphenoxy)-3,5-dimethylnitrobenzene → 4-(3-Bromo-4-methoxy-phenoxy)-3,5-dimethyl-phenylamine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-(3-Bromo-4-methoxyphenoxy)-3,5-dimethylnitrobenzene | HCID 22339728 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 溶媒 | Ethyl Acetate | HCID 8857 | — |
| 生成物 | 4-(3-Bromo-4-methoxy-phenoxy)-3,5-dimethyl-phenylamine | HCID 22339502 | 94% |
反応手順
A mixture of the title product of Step A (5.0 g) and 10% palladium on carbon (0.6 g) in ethyl acetate (100 ml) was hydrogenated at 50 psi for 3 h. The reaction was filtered through Celite and concentrated to afford the title compound of Step B as a yellow solid (4.3 g). MS (APCl+) Calc: 321; Found 322 (M+1).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06664291B2 |
| 出典データセット | uspto-grants-2003_12 |
| ORD ID | ord-414a861130a146b7acaea4be7d466a07 |
| 出典メモ | uspto-grants-2003_12 |