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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 433038Generated: October 25, 2026

3-[2-(2,4-Dichlorophenyl)ethoxy]-4-methoxybenzoic acid ethyl ester → 3-[2-(2,4-Dichlorophenyl)ethoxy]-4-methoxybenzoic acid

https://huagongshe.com/reaction/433038

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-[2-(2,4-Dichlorophenyl)ethoxy]-4-methoxybenzoic acid ethyl esterHCID 15480331—
SolventEthanolHCID 702—
SolventSodium HydroxideHCID 14798—
Product3-[2-(2,4-Dichlorophenyl)ethoxy]-4-methoxybenzoic acidHCID 1548033273%

Reaction Steps

A solution of 3.6 g (9.8 mmol) of 3-[2-(2,4-dichlorophenyl)ethoxy]4-methoxybenzoic acid ethyl ester in 30 ml of ethanol and 5.4 ml of 2N sodium hydroxide solution was stirred at room temperature for 12 h. The precipitate was filtered off. The resulting solid was stirred with 5 ml of 2N HCl and filtered to give 2.44 g (73%) of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06664393B2
Source datasetuspto-grants-2003_12
ORD IDord-34e3e639d5814b65982c9730a9c1df44
Source noteuspto-grants-2003_12