HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,1,1-Trimethoxypropane → HCID 22320470, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,1,1-Trimethoxypropane | HCID 141145 | — |
| Reactant | Pyridinium chloride | HCID 10176127 | — |
| Reactant | HCID 69895270 | HCID 69895270 | — |
| Product | HCID 22320470 | HCID 22320470 | 72.7% |
Reaction Steps
Using the general method of Example 1 Part D, N4-(4-chlorobutyl)quinoline-3,4-diamine (30 g, 0.12 mole) was cyclized using trimethyl orthopropionate (23.3 g, 0.13 mol) in the presence of a catalytic amount of pyridine hydrochloride to provide 25.1 g of 1-(4-chlorobutyl)-2-ethyl-1H-imidazo[4,5-c]quinoline as solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06667312B2 |
| Source dataset | uspto-grants-2003_12 |
| ORD ID | ord-b0e92f2fdffc4f688bc39977ffd1cdcf |
| Source note | uspto-grants-2003_12 |